| Bioactivity | [D-Trp34]-Neuropeptide Y TFA is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y TFA is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y TFA markedly increases food intake in rats[1][2]. |
| Invitro | [D-Trp34]-Neuropeptide Y TFA has pKi values of 6.49, 5.43, 7.08, 7.53, 6.55, 5.95, 6.85, 7.41 for hY1, hY2, hY4, hY5, rY1, rY2, rY4, rY5 in CHO cells. [D-Trp34]-Neuropeptide Y TFA has pEC50 values of 6.44, <6, 6.28,7.82 for rY1, rY2 in CHO cells and rY4, rY5 in HEK-293 cells[1]. |
| Name | [D-Trp34]-Neuropeptide Y TFA |
| Shortening | YPSKPDNPGEDAPAEDLARYYSALRHYINLITR-{D-Trp}-RY-NH2 |
| Formula | C198H290F3N55O58 |
| Molar Mass | 4425.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |